A new strategy for chiral drug synthesis through the discovery of novel organoboron compounds
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Affiliation
POSTECH Department of Chemistry
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E-Mail
seunghwan@postech.ac.kr
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Award-winning achievements
The objective of Professor Seunghwan Cho’s research is to design and synthesize novel polysubstituted organoboron compounds, as well as to develop methodologies that can convert these into chiral organoboron compounds. His research focuses on synthesizing a nitrogen-substituted 1,1-diboron compound with a chiral precursor to utilize it to promote the formation of a stereoselective carbon-carbon bonding. Through this, Professor Cho seeks to pioneer the field of chiral organoboron compound synthesis.
Nitrogen-substituted 1,1-diboron compounds did not exist before. They will likely be a reactive agent used in various fields for synthesizing chiral organoboron compounds for possible commercialization. Also, the novel methodology he intends to introduce based on this study is the convenient synthesis of natural and non-natural chirality-centered pharmaceuticals through high optical selectivity of chiral boron compound synthesis.
This study is challenging but presents high synthetic applicability and should play a pivotal role in the future synthesis of various medicines, materials, and raw materials.